Drugs & Drug Economy (Version from Feb 22, 2026, 09:44 PM)

8 drug types — Complete catalog of every drug available for production and sale on Isla Sombra in Drug Dealer Simulator 2, plus mixing formulas, overdose mechanics, and cutting agent rankings.

Data sourced from game files. Prices, potency values, and mixing stats may change with Early Access updates.

⚠️ Early Access — prices, potency values, and package sizes shown below are extracted from current game files and may change with future updates.

📑 Table of Contents

📊 Drug Overview
🌿 Marijuana (Weed)
⚡ Amphetamine
💎 Methamphetamine
❄️ Cocaine
💉 Opium
💉 Morphine
🌈 LSD
🍄 Shrooms
💰 Profitability Comparison
⚗️ Mixing Mechanics & Formulas
💀 Overdose Mechanics
⭐ Best Cutting Agents

📊 Drug Overview (8 drugs)

Drug	Avg Price/g	Form	Variants	Potency Range
Marijuana (Weed) `WEED`	$1,500	Dried herbs	2	0.83–0.91
Amphetamine `AMPH`	$2,200	Powder	1	0.86
Methamphetamine `METH`	$3,000	Crystal/Powder	2	0.88–0.95
Cocaine `COCAINE`	$7,000	Powder	1	0.89
Opium `OPIUM`	$2,200	Lump/Powder	2	0.80–0.83
Morphine `MORPHINE`	$5,000	Liquid (vials)	1	0.90
LSD `LSD`	$42,000	Blotter tabs/Liquid	2	0.83
Shrooms `SHROOMS`	$2,500	Dried mushrooms	2	0.79

🌿 Marijuana (Weed) (2 variants)

Cannabis dried flowers, sold in 10g–500g packages. Two strains: Indica and Sativa.

Substances

Substance	Potency	Price	Notes
Cannabis Indica `SUBSTANCE-WEED-IND`	0.83	$900/g (10g pack)	Slower growing, indoor-friendly
Cannabis Sativa `SUBSTANCE-WEED-SAT`	0.91	$1,200/g (10g pack)	Higher potency, outdoor growing

Craftable Products

Product	Value	Recipe
Weed Pipe	$2,000	0.5g weed + 0.5g tobacco + glass pipe
Blunt	$1,600	0.5g weed + 0.5g tobacco + rolling papers
Cookie (Funny)	$2,000 (×10)	5g weed + flour + sugar + soda
Hash	$2,500/piece	Cannabis powder → lump → hash

Package Prices

10g	50g	100g	500g
$9,000–$12,000	$45,000	$90,000–$120,000	$450,000

⚡ Amphetamine (1 variant)

Speed — processed from phenylethylamine via amphetamine salts. Multiple synthesis routes.

Substances

Substance	Potency	Price	Notes
Amphetamine `SUBSTANCE-AMPH`	0.86	$1,200/g (10g pack)	Standard amphetamine powder

Craftable Products

Product	Value	Recipe
Amph Vial	$3,000	1g amphetamine + vial

Package Prices

10g	50g	100g	500g
$12,000	$61,000	$120,000	$610,000

💎 Methamphetamine (2 variants)

Crystal meth — processed from ephedrine. Two tiers: standard meth and rare Blue Meth ("Smurf Dope").

Substances

Substance	Potency	Price	Notes
Methamphetamine `SUBSTANCE-METH`	0.88	$1,800/g (10g pack)	Standard crystal meth
Blue Meth (Smurf Dope) `SUBSTANCE-BLUE-METH`	0.95	$1,800/g (10g pack)	Premium variant from methylamine — highest potency

Craftable Products

Product	Value	Recipe
Meth Vial	$4,000	1g meth + vial

Package Prices

10g	50g	100g	500g
$18,000	$90,000	$180,000	$900,000

❄️ Cocaine (1 variant)

Processed from coca leaves through a multi-step chain: leaves → soft leaves → paste → cocaine.

Substances

Substance	Potency	Price	Notes
Cocaine `SUBSTANCE-COCAINE`	0.89	$2,400/g (10g pack)	Standard cocaine powder

Craftable Products

Product	Value	Recipe
Cocaine Vial	$7,000	1g cocaine + vial
Crack	$3,500/piece	Cocaine + ammonia/soda → crack lump → crack chunks

Package Prices

10g	50g	100g	500g
$24,000	$120,000	$240,000	$1,200,000

💉 Opium (2 variants)

Derived from poppy milk (from poppy heads or seeds). Can be further processed into morphine.

Substances

Substance	Potency	Price	Notes
Opium `SUBSTANCE-OPIUM`	0.83	$1,320/g (10g pack)	Standard opium lump
Opium powder `SUBSTANCE-OPIUM-POWDER`	0.80	—	Ground opium for mixing

Craftable Products

Product	Price	Recipe
Opium pipe	$2,200	0.5g opium + glass pipe

Package Prices

10g

$13,200

50g

$66,000

100g

$132,000

500g

$660,000

💉 Morphine (1 variant)

Advanced opiate — 4-step chain from opium. Sold in labeled medical vials or boxes. Highest addiction rating (0.7).

Substances

Substance	Potency	Price	Notes
Morphine `SUBSTANCE-MORPHINE`	0.90	$8,000/vial (5g)	Liquid morphine in labeled vials

Craftable Products

Product	Price	Recipe
Morphine vial	$8,000	5g morphine + empty medical vial
Morphine box (×50 vials)	$400,000	50 vials + medical box + duct tape

Package Prices

50g special pack

$20,000

Vial (5g)

$8,000

Box (50 vials)

$400,000

🌈 LSD (2 variants)

Most expensive drug per gram. Complex synthesis from ergotamine (rye, morning glory, or migraine medicine).

Substances

Substance	Potency	Price	Notes
LSD (liquid) `SUBSTANCE-LSD`	0.83	$42,000/g	Liquid LSD compound
LSD tab `DRUG-LSD-TAB`	—	$3,500/tab	Paper blotter soaked with LSD — 1g makes 10 tabs

Craftable Products

Product	Price	Recipe
LSD tab	$3,500	1 blotter + 1g LSD = 10 tabs

Package Prices

10 tabs

$19,000

50 tabs

$95,000

100 tabs

$190,000

500 tabs

$950,000

🍄 Shrooms (2 variants)

Psilocybin mushrooms — grow from spores, clean optional, dry for sale. Budget-friendly production.

Substances

Substance	Potency	Price	Notes
Dried shrooms (dirty base) `SUBSTANCE-SHROOMS-DRIED`	0.79	$250/g (10g pack)	Standard dried mushrooms
Powdered shrooms `SUBSTANCE-SHROOMS-POWDER`	0.79	—	Ground for mixing, retains potency

Package Prices

10g

$2,500

50g

$12,500

100g

$25,000

500g

$125,000

💰 Profitability Comparison (ranked by $/gram)

Approximate value per gram at base quality (no cutting agents), ranked from most to least profitable.

Rank	Drug	$/gram	Production Complexity	Tier
1	LSD	$42,000	Very High (4 steps + extraction)	T4
2	Cocaine	$7,000	High (4 steps from coca leaves)	T3
3	Morphine	$5,000	Very High (4 steps from opium)	T3
4	Methamphetamine	$3,000	High (3-4 steps from ephedrine)	T3
5	Blue Meth	$3,000+	High (requires methylamine)	T4
6	Shrooms	$2,500	Low (grow → dry)	T1-2
7	Amphetamine	$2,200	Medium (extraction → salts → amph)	T2
8	Opium	$2,200	Low (grow poppies → milk → lump)	T2
9	Marijuana	$1,500	Low (grow → dry)	T1-2

💡 LSD is by far the most profitable per gram ($42,000) but requires the most complex production chain and highest-tier equipment. For beginners, Marijuana and Shrooms offer the easiest entry point with minimal equipment investment.

⚗️ Mixing Mechanics & Formulas (how potency & stats work)

Every substance in DDS2 has up to four properties that affect the final mixed product. These are the stats you see on the Substances & Cutting Agents page.

Stat	Game Label	What It Does	Goal
Potency	POT / "Power"	The base strength of a drug substance (0.0–1.0). This is what customers evaluate against the town’s expected potency. Higher potency = better reputation. Cutting agents with a POT multiplier > 1.0 can increase final potency.	Higher is better
TOX	Toxicity	How dangerous the substance is. Directly feeds into the overdose chance formula. High-TOX cutting agents (acetone, gasoline, methanol) are lethal at high mix ratios. Only substances with a TOX value contribute to OD risk — zero-TOX fillers like flour, sugar, and salt do not increase OD chance.	Lower is better
ADD	Addiction	How addictive the substance is. Higher addiction = customers return more frequently for repeat purchases. However, addicted customers are more vulnerable to overdose, so you may need cleaner mixes for repeat buyers.	Higher for profit
STR	Strength / MixSTR	The strength multiplier (mixStrengthening). Values > 1.0 boost the final potency of the mixed product; values < 1.0 reduce it. This is the key stat for cutting agents — it determines whether your filler helps or hurts the product’s perceived quality. The game averages all ingredient STR values weighted by quantity.	≥ 1.0

Potency Calculation

Average Potency = Sum of (each substance’s Potency × grams used) ÷ Total grams in mix

Example: 80g Cocaine (0.89) + 20g Soda (0.0)
  = (0.89 × 80 + 0.0 × 20) ÷ 100 = 0.712 final potency

Each town/zone has a potency expectation. If your average potency exceeds the town’s expectation, your reputation increases. If it falls below, reputation drops. Pure (uncut) drugs always meet expectations — the trade-off of cutting is more volume for lower quality.

Mix Strength Formula

Mix STR Multiplier = Sum of (each ingredient’s STR × its volume) ÷ Total volume

Final Potency ≈ Average Potency × Mix STR Multiplier

Example: 80g Cocaine (STR 1.0) + 20g Cough Syrup (STR ~1.01)
  STR Mult = (1.0 × 80 + 1.01 × 20) ÷ 100 = 1.002
  Potency barely changes — Cough Syrup is a “neutral” filler that preserves quality.

💡 Key insight: Cutting agents with STR ≥ 1.0 (like cough syrup, migraine medicine, ethanol, or tobacco) let you stretch product volume without losing potency. Agents with STR < 1.0 (like baking soda at ~0.9) actively reduce your mix’s perceived quality, even though they’re safe.

💀 Overdose Mechanics (toxicity & OD chance)

Overdoses are calculated per-sale based on the toxicity of your mix and the quantity sold. Only substances with a TOX > 0 contribute to OD risk.

Toxicity Formula

Component Toxicity = Substance TOX × Quantity Sold × Mix Percentage

Average Toxicity = Sum of all Component Toxicities ÷ Total Grams Sold

Toxicity scales with the quantity sold per transaction. Selling 5g is far safer than selling 100g of the same mix. This means larger pack sizes carry proportionally higher overdose danger.

OD Chance Formula

OD Chance = (Avg Toxicity − 0.09) ÷ (0.4 − 0.09) × (0.75 − 0.05) + 0.05

The game clamps toxicity between two thresholds before calculating OD probability:

Threshold	Value	Meaning
Minimum TOX Level	0.09	Below this, toxicity is treated as 0.09 (baseline risk always exists)
Maximum TOX Level	0.40	Above this, OD chance is capped at maximum
Minimum OD Chance	5%	Every sale has at least a 5% OD chance (risk is never zero)
Maximum OD Chance	75%	The worst possible OD rate at maximum toxicity

⚠ Addicted customers are more vulnerable. Even relatively safe products can cause ODs if sold to addicted buyers in large quantities over time. Consider offering cleaner mixes to long-term repeat customers.

⭐ Best Cutting Agents (ranked by safety & effectiveness)

Not all fillers are equal. The best cutting agents preserve potency (STR ≥ 1.0) while keeping toxicity at zero. Here are the cutting agents from the Substances page, ranked by mix safety.

🟢 Tier 1 — Safe & Potency-Preserving (best mixers)

Zero or near-zero toxicity with STR ≥ 1.0. These agents let you stretch product without losing quality or killing customers.

Agent	TOX	POT	ADD	STR	Why It’s Good
Cough Syrup	—	1.01	0.1	~1.0	Zero TOX, slight potency boost, mild addiction. Ideal filler.
Migraine Medicine	—	1.01	0.1	~1.0	Zero TOX, slight potency boost. Same tier as cough syrup.
Tobacco / Powdered Tobacco	—	1.01	0.1	1.05	Zero TOX, STR > 1.0 actively boosts potency. Community favorite for amph mixes.
Vinegar	—	—	—	—	Zero TOX, zero everything. Pure bulk filler — dilutes potency but never kills.

🟠 Tier 2 — Safe Fillers (low risk, dilutes potency)

Zero or very low TOX, but STR < 1.0 or no potency boost. Good for volume but customers may notice reduced quality.

Agent	TOX	POT	ADD	STR	Notes
Flour	—	—	—	—	Cheap, zero TOX. Dilutes potency — good for beginners.
Sugar	—	—	—	—	Zero TOX, zero stats. Pure bulk filler.
Salt	—	—	—	—	Zero TOX. Common in multi-ingredient mixes (flour + salt combos).
Soda (Baking Soda)	0.1	—	—	~0.9	Very low TOX, but STR < 1.0 actively hurts potency. The classic cheap filler.

🔴 Tier 3 — Dangerous (high risk, handle with care)

High TOX, but strong STR multipliers. These can boost potency at the cost of killing your customers. Use in small amounts only.

Agent	TOX	POT	ADD	STR	Warning
Ethanol	0.2	—	0.1	1.05	Moderate TOX but good STR. Usable in small amounts.
Ammonia	0.4	—	—	—	High TOX, no benefits. Used in crack production only.
Acetone	0.7	—	—	—	Very high TOX. Required for liquid mixing — evaporates during crystallization.
Gasoline	0.9	—	—	—	Extremely toxic. Used in cocaine processing, not for cutting.
Washing Powder	0.7	—	—	—	Highly toxic, no upside. Avoid as a cutting agent.

Community-Tested Recipes

Popular mixes reported by the DDS2 community. Results may vary with game updates.

Drug	Recipe	Rating	Notes
Amphetamine	76% amph + 24% soda	Safe	Classic budget cut. Soda’s low STR reduces potency slightly.
Amphetamine	50% amph + 50% powdered tobacco	⭐ Best	Zero TOX, STR > 1.0 preserves potency. No reported ODs.
Amphetamine	77% amph + 12% flour + 11% salt	Safe	Multi-filler approach. Zero TOX but dilutes potency.
Cocaine	80% coke + 20% cough syrup	⭐ Best	Cough syrup’s POT 1.01 and zero TOX preserve quality.

💡 TL;DR for best mixers: Use powdered tobacco, cough syrup, or migraine medicine as your primary cutting agents. They have zero toxicity and STR/POT ≥ 1.0, meaning they stretch your product without reducing quality or risking overdoses. Avoid baking soda if quality matters — its STR of ~0.9 actively lowers potency.

Data extracted from DDS2 game files. Prices shown are base values before cutting agent modifiers. Mixing formulas sourced from community research and game code analysis. Early Access — values may change with updates.